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VIROLFI 450 INJ
1850.0 INR/Number
Product Details:
- Origin of Medicine India
- Dosage Form Injection
- Indication Treatment of systemic fungal infections including mucormycosis and aspergillosis
- Salt Composition Liposomal Amphotericin B 50 mg
- Brand Name Virolfi 450 Inj
- Life Span 24 months from the date of manufacture
- Pacakaging (Quantity Per Box) 1 vial per box
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VIROLFI 450 INJ Price And Quantity
- 1 Number
- 1850.0 INR/Number
- Antifungal
- Yes, before administration
- Intravenous (IV)
- Yes
- Liposomal formulation for reduced nephrotoxicity
- Known hypersensitivity to Amphotericin B or other formulation components
- WHO GMP certified manufacturing
- Infusion-related reactions, nephrotoxicity, electrolyte imbalance
- Yellowish suspension
- 24 months
VIROLFI 450 INJ Product Specifications
- Adults
- Vial
- Allopathic Injection
- 1 vial per box
- 24 months from the date of manufacture
- Virolfi 450 Inj
- Liposomal Amphotericin B
- Liposomal Amphotericin B 50 mg
- Intravenous use only. Follow doctors prescription.
- Store below 25C, protect from light
- Treatment of systemic fungal infections including mucormycosis and aspergillosis
- Patients with fungal infections requiring systemic antifungal therapy
- Injection
- 1 Vial
- India
- To be administered as per physicians advice
- Systemic antifungal therapy
- Liquid Injection
- Antifungal
- Yes, before administration
- Intravenous (IV)
- Yes
- Liposomal formulation for reduced nephrotoxicity
- Known hypersensitivity to Amphotericin B or other formulation components
- WHO GMP certified manufacturing
- Infusion-related reactions, nephrotoxicity, electrolyte imbalance
- Yellowish suspension
- 24 months
VIROLFI 450 INJ Trade Information
- Cash on Delivery (COD), Cash Advance (CA), Cash in Advance (CID)
- 1000 Number Per Week
- 2 Days
- No
- Asia, Australia, Central America, North America, South America, Africa, Eastern Europe, Western Europe, Middle East
- All India
Product Description
Virolfi 450 mg is prescribed for two main purposes:
- Treatment of CMV Retinitis: It is used in adult patients with Acquired Immunodeficiency Syndrome (AIDS) to treat cytomegalovirus infection of the retina (retinitis), which is a serious eye infection that can lead to vision problems and blindness.
- Prevention of CMV Infection: It helps prevent CMV disease in patients who have received a solid organ transplant (such as a kidney, heart, or pancreas) from a donor who was CMV-positive.
How it Works
The medication works by being converted into ganciclovir within the body. Ganciclovir is the active form, which then inhibits the multiplication of the virus in human cells, effectively stopping the infection from producing new viruses and spreading.
Important Considerations
- Administration: Virolfi 450 mg tablets should be swallowed whole, not crushed or chewed, and taken with food to improve absorption.
- Dosage: The dose and duration are determined by a doctor and depend on the patient's condition and response to treatment.
- Side Effects: Common side effects include diarrhea, headache, nausea, vomiting, fever, fatigue, and low blood cell counts (anemia, low white blood cells, low platelets).
- Precautions:
- It may cause bone marrow suppression, requiring regular blood tests to monitor cell counts.
- It is generally not recommended during pregnancy or breastfeeding due to potential harm to the baby.
- Effective contraception is essential during and for a period after treatment for both men and women.
- Patients with kidney problems may need a dosage adjustment.
- Patients should drink plenty of water to stay hydrated and reduce the risk of kidney damage.
Advanced Liposomal Technology for Safety
Virolfi 450 Inj leverages liposomal technology to encapsulate Amphotericin B, significantly minimizing the risk of kidney damage commonly associated with conventional amphotericin therapies. This formulation increases drug delivery efficiency and enhances patient safety by reducing infusion-related adverse effects, making it suitable for prolonged antifungal therapy in adults.
Comprehensive Antifungal Spectrum
Designed for patients with systemic fungal infections, Virolfi 450 Inj effectively targets a broad range of pathogens, including those responsible for mucormycosis and aspergillosis. Its intravenous administration ensures rapid and potent action, which is critical for patients needing immediate and robust systemic antifungal intervention, as prescribed by their doctor.
Strict Quality Standards and Certifications
Virolfi 450 Inj is manufactured in India under stringent WHO Good Manufacturing Practice (GMP) conditions, ensuring high quality and safety. The product is distributed in a single-use vial, guaranteeing sterility and optimal therapeutic effect. Its 24-month shelf life supports reliable storage and timely use in healthcare settings.
FAQ's of VIROLFI 450 INJ:
Q: How should Virolfi 450 Inj be administered for antifungal treatment?
A: Virolfi 450 Inj is administered intravenously after reconstitution with a suitable diluent by a healthcare professional, strictly following the dosage and schedule prescribed by your doctor. It is not intended for self-administration or any non-IV route.Q: What are the main benefits of the liposomal formulation in Virolfi 450 Inj?
A: The liposomal formulation significantly reduces the risk of nephrotoxicity (kidney damage) and infusion-related reactions compared to conventional amphotericin B. This allows for safer systemic antifungal therapy, especially in patients requiring prolonged treatment.Q: When is Virolfi 450 Inj recommended for use?
A: Virolfi 450 Inj is recommended for adults diagnosed with severe systemic fungal infections such as mucormycosis or aspergillosis, as determined by their physician. The medication is indicated when systemic, rapid antifungal therapy is necessary.Q: What steps are involved in preparing Virolfi 450 Inj for administration?
A: Before administration, the lyophilized powder must be carefully reconstituted with the appropriate amount of sterile water or specified diluent, followed by further dilution as per guidelines. The preparation should be done under aseptic conditions by qualified medical staff.Q: What precautions should be taken regarding the storage and handling of Virolfi 450 Inj?
A: Store Virolfi 450 Inj below 25C and protect it from light. The reconstituted solution should be used immediately. Keep the product out of reach of children and only let qualified personnel handle and administer it.Q: Who should not use Virolfi 450 Inj?
A: Virolfi 450 Inj is contraindicated in patients with known hypersensitivity to Amphotericin B, liposomal formulations, or any ingredients contained in the product. Inform your doctor about any allergies before starting treatment.Tell us about your requirement
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