Product Description
Trastuzumab is a medication used to treat certain types of cancer, notably HER2-positive breast cancer and HER2-positive metastatic gastric or gastroesophageal junction adenocarcinoma. It is a monoclonal antibody that targets the HER2 protein, which is overexpressed in some cancer cells.
The dosage of trastuzumab can vary depending on factors such as the specific type and stage of cancer being treated, as well as the patients weight and overall health. Trastuzumab is typically administered as an intravenous (IV) infusion.
For HER2-positive breast cancer, the dosage might be 440 mg given initially as a loading dose, followed by subsequent doses at a lower maintenance dosage. The treatment schedule can vary depending on whether trastuzumab is used in combination with other chemotherapy drugs or as a standalone therapy.
As with any medication, its important to follow the dosage and administration instructions provided by your healthcare provider. They will tailor the treatment plan to your specific needs and monitor you for any potential side effects.
Mechanism and FunctionTrastuzumab is a monoclonal antibody that specifically targets and binds to the HER2 receptor, which is found in higher quantities on certain cancer cells. By doing so, it blocks the growth signals, helping to slow or stop the progression of HER2-positive breast and gastric cancers. This targeted action makes Trastuzumab an important therapy in oncology.
Preparation and AdministrationThis medication is formulated as a lyophilized powder that needs to be reconstituted with sterile water before being administered intravenously. Only healthcare professionals should handle preparation and infusion, ensuring accurate dosing and patient safety. Strict adherence to physician instructions is crucial throughout the treatment process.
Storage and PackagingTrastuzumab for Injection should be stored in a cool, dry place and protected from light to maintain its efficacy. The product comes in vials, each usually packed individually per box, with strengths of either 150 mg or 440 mg. Always check expiration dates and storage instructions prior to use.
FAQs of Trastuzumab For Injection:
Q: How should Trastuzumab for Injection be prepared before administration?
A: Trastuzumab for Injection requires reconstitution with sterile water for injection. Only trained healthcare professionals should handle its preparation and intravenous administration to ensure correct dosing and patient safety.
Q: What types of cancer is Trastuzumab recommended for?
A: Trastuzumab is indicated for adults with HER2-positive metastatic breast cancer and HER2-positive gastric cancer. It specifically targets the HER2 receptor, making it effective in cases where this receptor is overexpressed.
Q: When should Trastuzumab treatment be initiated?
A: Treatment with Trastuzumab should be started only after confirming HER2-positive status in the patient, and in accordance with a physicians assessment and dosage guidelines appropriate for the cancer type being treated.
Q: Where should Trastuzumab vials be stored prior to use?
A: Keep Trastuzumab vials in a dry and cool place, away from direct sunlight. Proper storage helps maintain the medications stability for up to 24 months from the manufacturing date.
Q: What is the process for using Trastuzumab for Injection?
A: After confirming the patients HER2-positive status, the physician prescribes the appropriate dosage. A healthcare provider reconstitutes the powder with sterile water and administers it via intravenous infusion under clinical supervision.
Q: What benefits does Trastuzumab provide to patients?
A: Trastuzumab selectively targets the HER2 receptor present in certain cancer cells, interfering with their growth and proliferation. This targeted approach can improve outcomes for patients with HER2-positive cancers when used as part of a prescribed regimen.
Q: Who can supply or distribute Trastuzumab for Injection in India?
A: Trastuzumab is available through various licensed dealers, distributors, exporters, manufacturers, retailers, suppliers, traders, and wholesalers across India. It is a prescription medicine and should be sourced from authorized channels.