PERZEA 420MG

24999.0 INR/Box

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Product Details:

Origin of Medicine INDIA
Drug Type Injection
Ingredients Active IngredientPertuzumab: \(420\text{ mg}\) per \(14\text{ mL}\) vial (concentration of \(30\text{ mg/mL}\)). It is a humanized monoclonal antibody produced via recombinant DNA technology in mammalian (Chinese hamster ovary) cells.Inactive Ingredients (Excipients)Glacial acetic acid: Helps maintain a stable, optimal pH for the solution.L-Histidine: An amino acid that acts as a buffering agent to stabilize the protein.Sucrose: A sugar used as a cryoprotectant to protect the antibodies during storage.Polysorbate 20: A surfactant that prevents the antibody from aggregating or sticking to the vial surfaces.Water for injections: The sterile liquid solvent used to dissolve and dilute the ingredients.
Physical Form Liquid
Dosage 420
Suitable For Women, Adults
Quantity 1 Boxes
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PERZEA 420MG Price And Quantity

Minimum Order Quantity 10 Box
Price 24999.0 INR/Box

PERZEA 420MG Product Specifications

Physical Form Liquid
Dosage 420
Suitable For Women, Adults
Drug Type Injection
Ingredients Active IngredientPertuzumab: \(420\text{ mg}\) per \(14\text{ mL}\) vial (concentration of \(30\text{ mg/mL}\)). It is a humanized monoclonal antibody produced via recombinant DNA technology in mammalian (Chinese hamster ovary) cells.Inactive Ingredients (Excipients)Glacial acetic acid: Helps maintain a stable, optimal pH for the solution.L-Histidine: An amino acid that acts as a buffering agent to stabilize the protein.Sucrose: A sugar used as a cryoprotectant to protect the antibodies during storage.Polysorbate 20: A surfactant that prevents the antibody from aggregating or sticking to the vial surfaces.Water for injections: The sterile liquid solvent used to dissolve and dilute the ingredients.
Origin of Medicine INDIA
Quantity 1 Boxes

Product Description

Actionable & Authoritative Resources

For detailed prescribing information, dosage guidelines, and patient resources, consult these authoritative platforms:

Product Label: Access complete FDA-approved guidelines on the U.S. Food and Drug Administration.
Clinical Overview: Read detailed pharmacology and indications via Medscape.
Supplier Information: View specifications and distribution details on 1mg or Apothecare.

Key Characteristics

Mechanism of Action: Pertuzumab binds to a specific site on the HER2 receptor (subdomain II). This prevents the HER2 protein from pairing (dimerizing) with other HER receptors, ultimately stopping the cancer cells from growing and multiplying.
Dosage Schedule: The 420 mg strength serves as a maintenance dose. It is typically administered after an initial 840 mg loading dose. The maintenance infusion takes 30 to 60 minutes and is repeated every 3 weeks.
Indications: Used in early-stage HER2-positive breast cancer (before or after surgery) and metastatic HER2-positive breast cancer.
Side Effects: Common side effects include diarrhea, hair loss (alopecia), nausea, fatigue, and a decrease in certain white blood cells (neutropenia). It may also cause infusion-related reactions and heart function issues (e.g., left ventricular dysfunction).

Important Safety Information

Pregnancy Risk: Pertuzumab can cause embryo-fetal toxicity and birth defects. It is not recommended during pregnancy. Effective contraception must be used during treatment and for at least 6 months after the final dose.
Heart Monitoring: Because of the risk of heart muscle damage, healthcare providers routinely monitor heart function before and during treatment.
Administration: This medication must only be prepared and administered by a qualified healthcare professional in a clinical setting.

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