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LUPIHER2 420MG INJ
45000.0 INR/Number
Product Details:
- Pacakaging (Quantity Per Box) 1 vial per box
- Dosage Form Injection (Lyophilized Powder for Solution)
- Brand Name LUPIHER2
- Life Span Refer to expiry date on vial
- Salt Composition Trastuzumab
- Indication Treatment of HER2-positive breast and gastric cancers
- Origin of Medicine India
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LUPIHER2 420MG INJ Price And Quantity
- 45000.0 INR/Number
- 1 Number
- Prescription only (Rx)
- Anti-neoplastic agents
- Fever, chills, infusion reactions, cardiotoxicity, rash
- Not included
- Inform about possible infusion reactions and cardiac monitoring
- 420 mg per vial
- Lupin Limited
- Typically 24 months from manufacture
- Intravenous
- To be used under medical supervision only
- Sterile water for injection
- HER2/neu receptor
- Requires reconstitution before administration
- Hypersensitivity to trastuzumab or any excipients
LUPIHER2 420MG INJ Product Specifications
- Antineoplastic/Anti-cancer
- Injection
- As directed by physician (IV infusion)
- Injection (Lyophilized Powder for Solution)
- HER2-positive breast cancer and HER2-positive metastatic gastric cancer
- Biologic/Monoclonal Antibody
- 1 vial per box
- Adults
- Vial
- India
- Treatment of HER2-positive breast and gastric cancers
- Trastuzumab
- 420mg per vial
- Trastuzumab (Her2 Monoclonal Antibody) 420 mg
- Administer under supervision of qualified healthcare professional
- Refer to expiry date on vial
- LUPIHER2
- Store at 2C to 8C. Do not freeze. Protect from light.
- Prescription only (Rx)
- Anti-neoplastic agents
- Fever, chills, infusion reactions, cardiotoxicity, rash
- Not included
- Inform about possible infusion reactions and cardiac monitoring
- 420 mg per vial
- Lupin Limited
- Typically 24 months from manufacture
- Intravenous
- To be used under medical supervision only
- Sterile water for injection
- HER2/neu receptor
- Requires reconstitution before administration
- Hypersensitivity to trastuzumab or any excipients
LUPIHER2 420MG INJ Trade Information
- Cash on Delivery (COD), Cash Advance (CA), Cash in Advance (CID)
- 1000 Number Per Week
- 2 Days
- No
- Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
- All India
Product Description
- Active Ingredient: Pertuzumab is the active substance.
- Mechanism of Action: It is a humanized monoclonal antibody that targets the Human Epidermal Growth Factor Receptor 2 (HER2) protein found on the surface of cancer cells. By binding to a specific domain on the HER2 receptor, it blocks the protein from pairing with other HER family receptors (a process called dimerization), which inhibits cell growth signals and can lead to the destruction of cancer cells.
- Uses: Lupiher2 (pertuzumab) is used in several treatment contexts for HER2-positive breast cancer:
- Metastatic Breast Cancer: For cancer that has spread, in patients who have not received previous anti-HER2 treatment.
- Neoadjuvant Treatment: Given before surgery to shrink tumors in locally advanced, inflammatory, or early-stage breast cancer with a high risk of recurrence.
- Adjuvant Treatment: Given after surgery to reduce the risk of the cancer returning in early-stage cases at high risk of recurrence.
- Administration: It is administered by a healthcare professional as an intravenous infusion, typically once every three weeks. It is not for self-administration.
- Common Side Effects: Side effects can include diarrhea, hair loss (alopecia), nausea, fatigue, rash, and a sore mouth.
- Serious Warnings: It can cause heart-related problems (such as decreased heart function), severe allergic or infusion reactions, and low white blood cell counts. Patients are monitored closely for these issues.
- Pregnancy and Contraception: Lupiher2 is not recommended during pregnancy as it may harm the fetus. Effective contraception is required during treatment and for at least six months after the last dose.
Precision Therapy for HER2-positive Cancer
LUPIHER2 420MG INJ is designed for patients with HER2-positive breast and gastric cancers. Its active ingredient, trastuzumab, is a monoclonal antibody that specifically binds to HER2 receptors, inhibiting cancer cell growth. The formulation offers targeted treatment, potentially improving outcomes and minimizing effects on non-cancerous cells when administered as directed.
Administration and Handling Guidelines
This medication is supplied as a lyophilized powder in a vial and must be reconstituted with sterile water before intravenous infusion. The injection should only be prepared and administered by healthcare professionals in clinical settings, ensuring precise dosing and monitoring. Patients must not attempt self-administration under any circumstances.
Storage and Safety Precautions
LUPIHER2 should be stored in a refrigerator at 2C to 8C, protected from light, and must not be frozen. Always check the expiry date on the packaging before use. The medicinal product is for single-use only, and needles are not included in the pack.
FAQ's of LUPIHER2 420MG INJ:
Q: How is LUPIHER2 420MG INJ prepared and given to patients?
A: LUPIHER2 420MG INJ is first reconstituted by a healthcare professional using sterile water for injection. After reconstitution, it is administered as an intravenous infusion under the direct supervision of a qualified medical practitioner.Q: What conditions is LUPIHER2 420MG INJ used to treat?
A: LUPIHER2 is indicated for the treatment of adults with HER2-positive breast cancer and HER2-positive metastatic gastric cancer, as determined by appropriate diagnostic testing.Q: When should LUPIHER2 not be used?
A: LUPIHER2 is contraindicated in individuals with known hypersensitivity to trastuzumab or any of the excipients. It should not be used outside of medical supervision or in patients where the risks outweigh the potential benefits.Q: Where should LUPIHER2 be stored before use?
A: This medication should be stored in a refrigerator at a temperature between 2C and 8C, away from light. It must not be frozen, and the expiry date on the vial should always be checked prior to use.Q: What side effects should patients be aware of while using LUPIHER2?
A: Common side effects include fever, chills, infusion reactions, rash, and cardiotoxicity. Patients should report any unusual symptoms to their doctor and may require regular cardiac monitoring during treatment.Q: What is the process for administering LUPIHER2 and why is monitoring necessary?
A: LUPIHER2 is given as an intravenous infusion in a clinical setting. Monitoring is essential to quickly detect and manage potential infusion reactions and cardiotoxicity, ensuring the patient's safety.Q: What are the benefits of using LUPIHER2 420MG INJ?
A: LUPIHER2 provides targeted cancer therapy by blocking the HER2 receptor, potentially leading to improved outcomes for patients with HER2-positive cancers. Its precision mechanism reduces the risk of damaging healthy cells compared to less targeted treatments.Tell us about your requirement
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