Mechanism of Action: Pegfilgrastim encourages the bone marrow to produce more neutrophils, a type of white blood cell essential for the body's immune system to fight off bacterial infections.
Uses:
Reducing the incidence and duration of neutropenia (low white blood cell count) caused by myelosuppressive anti-cancer drugs.
Decreasing the risk of developing febrile neutropenia (fever with a low white blood cell count).
Increasing survival rates in patients exposed to high doses of radiation that damage bone marrow.
Administration: It is administered as a single subcutaneous (under the skin) injection once per chemotherapy cycle, typically at least 24 hours after the last dose of chemotherapy.
Common Side Effects: The most common side effects include bone pain, joint pain, headache, nausea, and pain or redness at the injection site.
Important Precautions:
Inform your doctor if you have sickle cell disease, kidney problems, or lung issues, as this medication may worsen these conditions.
Do not receive Pegstim within 14 days before or 24 hours after your chemotherapy dose.
Seek immediate medical attention if you experience signs of an allergic reaction (rash, swelling, difficulty breathing) or signs of an enlarged spleen (left upper abdominal pain or shoulder pain).
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