Cizumab is a recombinant humanized monoclonal antibody that functions as an anti-angiogenic agent. It works by:
Targeting VEGF:It selectively binds to a protein in the body called vascular endothelial growth factor (VEGF).
Inhibiting Blood Vessel Growth:VEGF usually stimulates the formation of new blood vessels (angiogenesis) that supply oxygen and nutrients to tumors, allowing them to grow and spread.
Starving the Tumor:By blocking the function of VEGF, Cizumab cuts off the tumor's blood supply, which in turn slows its growth, causes it to shrink, or induces cell death.
Key Uses
Cizumab 400 mg injection is primarily used to treat several types of cancer, usually in combination with other cancer therapies:
Metastatic cancer of the colon and rectum
Advanced non-small cell lung cancer
Kidney cancer (renal cell carcinoma)
Brain tumors (glioblastoma multiforme)
Ovarian, fallopian tube, or primary peritoneal cancer
Metastatic cervical cancer
Liver cancer (hepatocellular carcinoma)
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