Product Description
Darunavir is an antiretroviral medication used in the treatment of HIV/AIDS. It belongs to the class of drugs known as protease inhibitors. Darunavir works by inhibiting the activity of the protease enzyme, which is necessary for the HIV virus to replicate and spread within the body.
Darunavir is typically available in tablet form, and the usual dosage for adults is 600 mg taken orally once daily with ritonavir 100 mg. Ritonavir is often used as a "booster" medication to increase the levels of darunavir in the body by inhibiting its metabolism. This combination is commonly used in HIV treatment regimens to enhance the effectiveness of darunavir.
It's important to take darunavir exactly as prescribed by your healthcare provider and to not miss any doses. Skipping doses or not taking the medication as directed can lead to decreased effectiveness and potential development of drug resistance.
As with any medication, darunavir may cause side effects, and it's essential to be aware of these and report any unusual symptoms to your healthcare provider. Common side effects may include gastrointestinal disturbances, changes in liver function tests, and interactions with other medications.
If you have any questions or concerns about darunavir or its use, you should consult your healthcare provider or pharmacist for guidance. They can provide you with personalized advice based on your specific medical history and treatment needs.
How does Darunavir work in HIV treatment?Darunavir inhibits the HIV protease enzyme, preventing the maturation of viral particles in HIV-1. This mechanism helps control the virus and significantly improves the effectiveness of antiretroviral therapy when used with other agents. Darunavir is recognized for its high oral bioavailability, contributing to consistent blood levels and reliable treatment outcomes.
What are the possible side effects and contraindications?Common side effects of Darunavir include rash, diarrhea, nausea, and headache. It is contraindicated in individuals with hypersensitivity to Darunavir or any excipients in the tablet. Any allergic reactions or unexpected symptoms should be reported to your physician promptly.
Storage, Packaging, and Compliance StandardsDarunavir Tablets should be stored below 30C in a dry place, away from moisture. Each tablet comes in either HDPE bottles or blister packs, ensuring protection and convenience. The product is manufactured in facilities compliant with WHO GMP, US FDA, and EMEA guidelines, ensuring high quality and safety standards.
FAQ's of Darunavir Tablets:
Q: How should Darunavir Tablets be taken for HIV-1 treatment?
A: Darunavir Tablets are taken orally, usually once daily at the dose prescribed by your physician. They must always be used in combination with other antiretroviral medications for effective HIV-1 management. Follow your doctor's instructions carefully and take the tablets at the same time each day.
Q: What benefits does Darunavir offer in antiretroviral therapy?
A: Darunavir provides robust inhibition of HIV protease, reducing the replication of the virus. Its high oral bioavailability and film-coated formulation help ensure effective absorption and patient compliance in combination therapy for HIV-1 infection.
Q: When should Darunavir not be used?
A: Darunavir is contraindicated in patients with known hypersensitivity to Darunavir, Darunavir Ethanolate, or any of the excipients in the formulation. Always inform your doctor of any allergies before starting this medication.
Q: Where is Darunavir manufactured and what are the compliance standards?
A: Darunavir Tablets are produced in India by manufacturers operating under WHO GMP, US FDA, and EMEA-approved facilities. This guarantees that the tablets meet stringent safety and quality requirements for export and domestic supply.
Q: What should I do if I miss a dose of Darunavir?
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take two doses at once. For specific guidance, consult your healthcare provider.
Q: How should Darunavir Tablets be stored?
A: Store Darunavir Tablets below 30C in their original packaging to protect them from moisture. Keep them out of the reach of children and dispose of any expired medication properly.
Q: Can Darunavir be used in pediatric patients?
A: Darunavir may be used in pediatric patients, but the dosage and regimen must be determined by a physician. It is essential to consult a healthcare professional for appropriate pediatric dosing based on the child's age and weight.