Versavo 100 mg/4 mL Solution for Infusion contains Bevacizumab 100 mg, a recombinant humanized monoclonal antibody and anti-cancer biologic manufactured by Dr. Reddys Laboratories Ltd. It is supplied as a 4 mL vial (25 mg/mL) and is administered by intravenous infusion under medical supervision.
Bevacizumab works by inhibiting VEGF-A (vascular endothelial growth factor), thereby reducing the formation of new blood vessels that tumors need for growth and progression.
Versavo is indicated, depending on the approved regimen and cancer type, for conditions including metastatic colorectal cancer, advanced non-squamous NSCLC, recurrent glioblastoma, metastatic renal cell carcinoma, advanced cervical cancer, ovarian/fallopian tube/primary peritoneal cancers, and metastatic breast cancer.
| Particular | Details |
|---|---|
| Brand | VERSAVO 100 MG |
| Active Ingredient | Bevacizumab |
| Strength | 100 mg/4 mL |
| Dosage Form | Concentrate/Solution for IV infusion |
| Manufacturer | Dr. Reddys Laboratories Ltd. |
| Pack | 1 vial 4 mL |
| Storage | Refrigerate at 28C; do not freeze |
| Prescription | Prescription medicine |
1. What is Versavo 100 mg used for?
Versavo contains bevacizumab and is used with appropriate cancer treatment regimens for several advanced or metastatic cancers, including colorectal, lung, kidney, ovarian, cervical and certain brain cancers.
2. What is the composition of Versavo 100 mg?
Each 4 mL vial contains Bevacizumab 100 mg (25 mg/mL).
3. How is Versavo 100 mg administered?
It is administered as a slow intravenous infusion by a qualified healthcare professional. It should not be self-administered.
4. How does Versavo work?
It blocks VEGF-A, a protein involved in the formation of new blood vessels. This can reduce the blood supply supporting tumor growth.
5. Does Versavo require refrigeration?
Yes. It should generally be stored at 28C and should not be frozen.
6. What are common side effects?
Possible adverse effects include high blood pressure, protein in urine, fatigue, headache, nosebleeds and gastrointestinal symptoms.
7. Are there serious risks associated with bevacizumab?
Important risks can include serious bleeding, blood clots, gastrointestinal perforation, hypertension, kidney-related problems and impaired wound healing. Patients require appropriate medical monitoring.
8. Can Versavo be given before surgery?
Bevacizumab can affect wound healing, so its use around the time of surgery requires careful planning by the treating oncology team.
9. Is Versavo a prescription medicine?
Yes. It should be used only under the supervision and prescription of an appropriately qualified healthcare professional.
10. Is Versavo available in other strengths?
Yes. Versavo is available in 100 mg/4 mL and 400 mg/16 mL single-use vial presentations.
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