INTAZUMAB 420MG

Product Description

1. What is Intazumab 420 mg used for?
It is used in the treatment of HER2-positive breast cancer, including metastatic disease and certain early-stage settings before or after surgery.

2. What is the composition of Intazumab 420 mg?
Each vial contains Pertuzumab 420 mg in 14 mL (30 mg/mL).

3. Is Intazumab a chemotherapy medicine?
No. It is a targeted monoclonal-antibody therapy that targets the HER2 receptor. It is often used together with trastuzumab and chemotherapy as part of a treatment regimen.

4. How does Intazumab work?
Pertuzumab binds to HER2 and prevents HER2 from pairing with other HER-family receptors, thereby blocking signalling pathways involved in cancer-cell growth and survival.

5. How is Intazumab 420 mg administered?
It is given as an intravenous (IV) infusion by trained healthcare professionals. It should not be administered as an IV push or bolus.

6. What is the usual maintenance dose?
A commonly used regimen is an initial 840 mg loading dose, followed by 420 mg every 3 weeks, according to the oncologist's treatment protocol.

7. What are the common side effects?
Possible side effects include diarrhoea, nausea, vomiting, fatigue, rash, fever, hair loss and low blood-cell counts. Infusion-related reactions can also occur.

8. Can Intazumab affect the heart?
Yes. Pertuzumab can cause decreased heart function/left ventricular dysfunction. Patients may require cardiac monitoring, such as echocardiograms, during treatment.

9. What should I tell my doctor before treatment?
Inform the oncologist about any heart problems, previous cancer treatments, allergies, pregnancy, breastfeeding, or other medicines you are taking.

10. How should Intazumab 420 mg be stored?
Store refrigerated at 2C8C and do not freeze. Proper cold-chain handling is important.

11. Can Intazumab be used during pregnancy?
Pertuzumab can cause serious harm to a developing fetus. Pregnancy should be discussed with the oncologist before treatment, and appropriate contraception is generally advised during treatment and for the recommended period afterward.

12. Is Intazumab available only on prescription?
Yes. It is a prescription oncology medicine and should be administered under the supervision of an oncologist or qualified healthcare professional.