Netupitant And Palonostreron Capsules

5500 आईएनआर/Strip

मूल्य/उद्धरण प्राप्त करें

उत्पाद विवरण:

खुराक प्रपत्र Capsule
संकेत Prevention of chemotherapy-induced nausea and vomiting (CINV)
नमक की संरचना Netupitant 300mg + Palonosetron 0.5mg
फ़ीचर
सामग्रियां
एप्लीकेशन
भौतिक रंग/बनावट
अधिक देखने के लिए क्लिक करें
अपना उत्पाद साझा करें:

वापस कॉल करने का अनुरोध जांच भेजें

मूल्य और मात्रा

न्यूनतम आदेश मात्रा 5

Drug Interactions May interact with CYP3A4 substrates
Mechanism of Action Netupitant is an NK1 receptor antagonist; Palonosetron is a 5-HT3 antagonist
ATC Code A04AA55
CAS Number Netupitant: 555998-62-6, Palonosetron: 135729-62-3
Pregnancy Category Category B
Packaging Size 1 capsule per strip, pack of 1 or 4 strips
Prescription Status Prescription only (Rx)
Marketed By Available under various brands in India
Route of Administration Oral

उत्पाद की विशेषताएं

खुराक प्रपत्र Capsule
संकेत Prevention of chemotherapy-induced nausea and vomiting (CINV)
शेल्फ लाइफ 24 months
नमक की संरचना Netupitant 300mg + Palonosetron 0.5mg
स्टोरेज निर्देश Store below 30°C, protect from moisture

Drug Interactions May interact with CYP3A4 substrates
Mechanism of Action Netupitant is an NK1 receptor antagonist; Palonosetron is a 5-HT3 antagonist
ATC Code A04AA55
CAS Number Netupitant: 555998-62-6, Palonosetron: 135729-62-3
Pregnancy Category Category B
Packaging Size 1 capsule per strip, pack of 1 or 4 strips
Prescription Status Prescription only (Rx)
Marketed By Available under various brands in India
Route of Administration Oral

व्यापार सूचना

आपूर्ति की क्षमता प्रति सप्ताह
डिलीवरी का समय दिन
मुख्य घरेलू बाज़ार , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

उत्पाद वर्णन

Netupitant 300mg and Palonosetron 0.5mg are combined in a single capsule for the prevention of chemotherapy-induced nausea and vomiting (CINV). This combination therapy is often prescribed to patients undergoing chemotherapy treatment, as chemotherapy can frequently lead to nausea and vomiting, which can significantly impact the patient's quality of life.

Netupitant is a substance that belongs to the class of neurokinin-1 (NK-1) receptor antagonists. It works by blocking the action of substance P, a neurotransmitter in the brain that is involved in nausea and vomiting pathways. By inhibiting substance P, netupitant helps prevent nausea and vomiting triggered by chemotherapy.

Palonosetron is a selective serotonin (5-HT3) receptor antagonist. It functions by blocking the activity of serotonin, a neurotransmitter that plays a role in triggering nausea and vomiting in response to chemotherapy. Palonosetron is known for its long duration of action, which helps in providing extended protection against CINV.

When combined, netupitant and palonosetron provide enhanced prevention of both acute and delayed phases of chemotherapy-induced nausea and vomiting. This combination therapy is available in capsule form for oral administration and is typically taken prior to starting chemotherapy treatment according to the prescribing physician's instructions.

Here are some frequently asked questions (FAQs) about Netupitant and Palonosetron Capsules:

What are Netupitant and Palonosetron Capsules?Netupitant and Palonosetron Capsules are a combination medication used to prevent nausea and vomiting induced by chemotherapy, particularly for highly or moderately emetogenic (vomit-inducing) treatments.
How do Netupitant and Palonosetron Capsules work?Netupitant is a substance that blocks the action of neurokinin-1 (NK-1) receptors in the brain, which are involved in the vomiting reflex. Palonosetron is a serotonin (5-HT3) receptor antagonist that blocks serotonin, another neurotransmitter involved in the vomiting reflex. Together, they act synergistically to prevent nausea and vomiting.
What conditions do Netupitant and Palonosetron Capsules treat?These capsules are used to prevent acute and delayed nausea and vomiting associated with chemotherapy, particularly for patients undergoing highly emetogenic chemotherapy, as well as moderately emetogenic chemotherapy.
How are Netupitant and Palonosetron Capsules taken?They are typically taken orally as a single dose, usually about an hour before chemotherapy treatment. The capsules are swallowed whole with water and can be taken with or without food.
What are the common side effects of Netupitant and Palonosetron Capsules?Common side effects may include headache, constipation, fatigue, and dizziness. However, these side effects are generally mild and temporary.
Who should not take Netupitant and Palonosetron Capsules?Individuals with a known hypersensitivity to any of the components of the capsules should avoid taking them. It's essential to inform your healthcare provider about any allergies or medical conditions you have before starting treatment.
Can Netupitant and Palonosetron Capsules be taken during pregnancy or breastfeeding?There isn't enough data to determine the safety of these capsules during pregnancy or breastfeeding. It's crucial to discuss the potential risks and benefits with a healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
Are there any drug interactions with Netupitant and Palonosetron Capsules?Yes, these capsules can interact with other medications, including certain antibiotics, antifungals, and medications metabolized by the CYP3A4 enzyme system. It's important to inform your healthcare provider about all medications you are taking to avoid potential interactions.

Powerful Prevention for Chemotherapy-Induced Nausea

Combining the proven benefits of Netupitant and Palonosetron, this capsule offers comprehensive protection against both acute and delayed phases of chemotherapy-induced nausea and vomiting. The single-dose regimen simplifies administration, supporting better patient compliance and improved quality of life during cancer treatment.

Simple Oral Administration and Flexible Packaging

Administered orally, the capsule is easy to take and eliminates the need for injections or infusions. Available in single or multiple strip packs, it offers flexibility for different treatment plans and convenience for both patients and healthcare providers.

FAQ's of Netupitant And Palonostreron Capsules:

Q: How should Netupitant and Palonosetron Capsules be taken?

A: This capsule is taken orally, usually as a single dose prior to the start of chemotherapy. Follow your doctor's instructions carefully regarding the timing and method of intake.

Q: What is the main benefit of using this combination capsule for chemotherapy patients?

A: The combination of Netupitant and Palonosetron offers enhanced protection against chemotherapy-induced nausea and vomiting, covering both acute and delayed symptoms with a single, convenient dose.

Q: When should I take this capsule in relation to my chemotherapy session?

A: It is typically administered about one hour before chemotherapy begins. Always confirm the exact timing with your healthcare provider to achieve the best results.

Q: What storage precautions are recommended for this medication?

A: Store the capsules below 30C and protect them from moisture. Keep the strips in their original packaging until use to maintain drug stability throughout its shelf life of 24 months.

Q: Are there any significant drug interactions I should be aware of?

A: Yes, Netupitant may interact with medications that are substrates of CYP3A4. Inform your doctor about all the medicines you are taking to avoid potential interactions.

Q: Who manufactures and supplies this medicine in India?

A: This medicine is marketed under various brands and is available through dealers, distributors, exporters, manufacturers, retailers, suppliers, traders, and wholesalers throughout India.

Q: What is the appearance and odor of the capsule?

A: The capsule is a hard gelatin form, containing white or off-white powder, and is odorless, ensuring ease of use and no unpleasant smell during handling.