Rasburicase r DNA Origin

Product Description

1. What is Rasburicase (rDNA origin)?

   • Rasburicase is a medication used to treat and prevent high levels of uric acid in the blood, a condition known as hyperuricemia. It is a recombinant urate oxidase enzyme derived from DNA technology.

2. How does Rasburicase work?

   • Rasburicase works by converting uric acid into a more soluble compound called allantoin, which can be easily excreted by the kidneys. This helps to reduce uric acid levels in the blood and prevent complications such as kidney stones and gout.

3. What conditions is Rasburicase used to treat?

   • Rasburicase is primarily used to manage hyperuricemia associated with tumor lysis syndrome (TLS), a condition that can occur as a result of cancer treatment when cancer cells break down rapidly and release large amounts of uric acid into the bloodstream.

4. How is Rasburicase administered?

   • Rasburicase is administered intravenously (IV) by a healthcare professional in a hospital or clinical setting. The dosage and duration of treatment will depend on the patient's medical condition and response to therapy.

5. What are the common side effects of Rasburicase?

   • Common side effects may include allergic reactions (such as rash, itching, swelling, or difficulty breathing), headache, nausea, vomiting, fever, and abdominal pain. These side effects are usually mild and transient.

6. Are there any serious side effects I should be aware of?

   • Yes, Rasburicase can cause serious side effects, including severe allergic reactions (anaphylaxis), hemolysis (destruction of red blood cells), methemoglobinemia (a condition where the blood contains elevated levels of methemoglobin), and severe hypersensitivity reactions. Seek immediate medical attention if you experience any severe or persistent side effects.

7. Who should not receive Rasburicase?

   • Rasburicase should not be used in patients with a known allergy to rasburicase or any of the ingredients in the medication. It should also be used with caution in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency, as it may increase the risk of hemolysis.

8. Can Rasburicase interact with other medications?

   • Rasburicase may interact with certain medications, including other chemotherapy drugs and medications that affect kidney function. Inform your healthcare provider about all medications, supplements, and herbal remedies you are taking before starting Rasburicase treatment.

9. How should Rasburicase be stored?

   • It should be stored at room temperature (20-25C) away from light and moisture. Follow the specific storage instructions provided by your pharmacist.
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