Product Description
Pemnat 500mg Injection is used in thetreatment of non-small cell lung cancer and malignant pleural mesothelioma.
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What is Pemetrexed Injection?
- Pemetrexed injection contains the active ingredient pemetrexed disodium, which is a folate analog metabolic inhibitor. It works by interfering with the production of DNA and RNA necessary for the growth and replication of cancer cells.
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What conditions are treated with Pemetrexed Injection?
- Pemetrexed is used in the treatment of various types of cancer, including non-small cell lung cancer, malignant pleural mesothelioma, and certain types of metastatic or recurrent cancers, such as breast cancer and pancreatic cancer. It is typically used in combination with other chemotherapy drugs.
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How is Pemetrexed Injection administered?
- Pemetrexed injection is administered by intravenous (IV) infusion over a specified period, usually once every three weeks. The dosage and duration of treatment will depend on factors such as the type and stage of cancer, the patient's overall health, and their response to treatment.
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What are the possible side effects of Pemetrexed Injection?
- Common side effects of pemetrexed may include fatigue, nausea, vomiting, diarrhea, loss of appetite, and low blood cell counts (anemia, neutropenia, thrombocytopenia). More serious side effects can occur, including kidney problems, liver problems, lung problems, and severe skin reactions. It's essential to report any unusual symptoms to your doctor.
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Can Pemetrexed Injection be used during pregnancy or breastfeeding?
- Pemetrexed may cause harm to an unborn baby if used during pregnancy and is not recommended for use during pregnancy. It is also not recommended for use while breastfeeding as it may pass into breast milk and harm the nursing infant. Women of childbearing potential should use effective contraception during treatment and for a period of time after discontinuing the medication.
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Are there any medications that interact with Pemetrexed Injection?
- Pemetrexed can interact with certain medications, including other chemotherapy drugs and medications that affect kidney function or blood clotting. It's crucial to inform your doctor about all medications you are taking, including prescription, over-the-counter, and herbal supplements, to avoid potentially harmful interactions.
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How should Pemetrexed Injection be stored?
- Pemetrexed injection should be stored as directed by the manufacturer. Typically, it should be stored at room temperature away from light and moisture. Keep the medication out of reach of children and pets. Check the expiration date and properly dispose of any expired medication.
Broad-Spectrum Chemotherapy SupportPemetrexed Injection is designed as an effective chemotherapy agent primarily targeting malignant pleural mesothelioma and non-small cell lung cancer. Its proven efficacy and safety profile offer hope to patients undergoing complex cancer treatments by inhibiting cell growth pathways within tumors.
Quality, Safety, and ComplianceManufactured according to both USP and Indian Pharmacopeia standards, this sterile, single-use glass vial ensures stringent quality and compatibility with commonly used intravenous infusion solutions. Its cytotoxic nature demands careful handling and adherence to prescribed safety protocols.
Easy Storage and PreparationThe lyophilized powder form of Pemetrexed Injection is stable under recommended storage conditions-below 25C and protected from light. Reconstitution is straightforward for trained professionals, aiding in flexible clinical workflow and reliable therapeutic dosing.
FAQ's of Pemetrexed Injection:
Q: How should Pemetrexed Injection 500 mg be prepared for administration?
A: Pemetrexed Injection requires reconstitution before use. The lyophilized powder should be dissolved in sterile saline or as directed by the product label, followed by further dilution in standard IV infusion solutions, and is intended for intravenous (IV) administration by trained healthcare professionals.
Q: What conditions is Pemetrexed Injection indicated to treat?
A: This medication is prescribed for the treatment of malignant pleural mesothelioma and non-small cell lung cancer. It acts as an antineoplastic agent, interfering with cancer cell proliferation.
Q: When should cytotoxic handling precautions be followed with this product?
A: Cytotoxic precautions are necessary at all stages of handling-preparation, administration, and disposal of Pemetrexed Injection. Proper protective equipment should be used to minimize exposure risks to healthcare staff.
Q: Where should Pemetrexed Injection vials be stored to maintain stability?
A: Store unopened vials below 25C and protect from light. Adequate storage helps preserve the product's efficacy and extends its shelf life to 24 months.
Q: What are the benefits of using Pemetrexed Injection in chemotherapy protocols?
A: Pemetrexed Injection offers reliable therapeutic action against specific cancers, with standards-backed manufacturing ensuring patient safety. Compatibility with standard infusion solutions facilitates seamless integration into existing treatment regimens.
Q: What is the appearance and smell of Pemetrexed Injection before reconstitution?
A: Before reconstitution, the injection appears as a white to off-white lyophilized powder and is odorless, making it easy to identify and handle in clinical settings.