Odensomab (denosumab) belongs to a class of medicines called RANK ligand inhibitors. It functions by binding to a protein called the RANK ligand (RANKL), which is essential for the formation, function, and survival of osteoclasts (cells that break down bone tissue). By inhibiting RANKL, the medication reduces bone resorption (breakdown), thereby increasing bone mineral density and making bones stronger and less likely to fracture.
Key Uses
The 60 mg strength of Odensomab injection is used to manage several conditions:
Osteoporosis: Treatment of osteoporosis in postmenopausal women and men who are at high risk for fractures.
Bone Loss: To increase bone mass in patients with bone loss due to reduced hormone levels caused by certain cancer treatments (e.g., androgen deprivation therapy for prostate cancer or aromatase inhibitor therapy for breast cancer).
Giant Cell Tumor of the Bone (GCTB): To treat giant cell tumors of the bone by blocking specific receptors in the tumor cells, thus slowing their growth.
Hypercalcemia: To treat high calcium levels in the blood caused by cancer when other treatments have failed.
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