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GRAFALON INJ
29000.0 आईएनआर/Number
उत्पाद विवरण:
- खुराक प्रपत्र Injection
- नमक की संरचना Rabbit immunoglobulin against human T-lymphocytes
- मेडिसिन की उत्पत्ति Germany
- पैकेजिंग (मात्रा प्रति बॉक्स) 1 vial per box
- लाइफ स्पैन Shelf life of 24 months
- संकेत Prevention and treatment of steroid-resistant acute rejection after solid organ transplantation
- पैकेजिंग का प्रकार Glass vial
- अधिक देखने के लिए क्लिक करें
X
मूल्य और मात्रा
- 1
- Colourless to pale yellow solution
- 30021500
- May include leucopenia, thrombocytopenia, infusion reactions, infections
- Known hypersensitivity to rabbit proteins or to any of the excipients
- Prescription only
- Dr. Reddy's Laboratories
- Intravenous infusion
- L04AA03
उत्पाद की विशेषताएं
- Injection
- Prevention and treatment of acute rejection in organ transplantation
- One vial contains 5 ml (100 mg)
- Rabbit immunoglobulin against human T-lymphocytes
- Dosage as per physicians direction; typically infused intravenously
- GRAFALON
- Shelf life of 24 months
- Glass vial
- Prevention and treatment of steroid-resistant acute rejection after solid organ transplantation
- Store between 2C-8C. Do not freeze.
- 1 vial per box
- Germany
- Anti-human T lymphocyte immunoglobulin (rabbit) 20mg/ml
- Administered under strict medical supervision in a hospital setting
- Colourless to pale yellow solution
- 30021500
- May include leucopenia, thrombocytopenia, infusion reactions, infections
- Known hypersensitivity to rabbit proteins or to any of the excipients
- Prescription only
- Dr. Reddy's Laboratories
- Intravenous infusion
- L04AA03
व्यापार सूचना
- , ,
- प्रति सप्ताह
- दिन
- No
- , , , , , , , ,
उत्पाद वर्णन
- Active Ingredient: Human rabbit anti-T cell immunoglobulin, also known as anti-human T-lymphocyte globulin (ATLG).
- Mechanism of Action: It works by targeting and suppressing specific white blood cells, primarily T lymphocytes, which are responsible for identifying and attacking the transplanted cells or tissues as "foreign".
- Formulation: It is a concentrate for solution for infusion and must be diluted in 0.9% sodium chloride solution before intravenous administration. It is not for direct injection and should be administered over a period of at least 4 hours under strict medical supervision in a hospital setting.
- Storage: Vials should be stored in a refrigerator (2C - 8C or 36F - 46F) and kept in the outer carton to protect from light.
Key Uses
Grafalon is primarily used in combination with other immunosuppressive medicines for the following indications:
- Prevention of organ transplant rejection: To help the body accept solid organs such as kidneys.
- Treatment of acute organ transplant rejection: For rejection episodes that have not responded well to standard corticosteroid treatment.
- Prevention or treatment of severe Graft-versus-Host Disease (GvHD): A serious complication following bone marrow or stem cell transplants where the donor's immune cells attack the recipient's body.
- Treatment of Aplastic Anemia: A blood disorder where the bone marrow doesn't produce enough healthy blood cells.
Mechanism of Action
GRAFALON functions as an immunosuppressive agent by targeting and depleting human T lymphocytes. This action aids in reducing immune responses that lead to organ rejection, thereby increasing the success rate of transplantation procedures.
Indications and Clinical Use
This medication is recommended for the prevention and treatment of steroid-resistant acute rejection in adult patients who have undergone solid organ transplantation. Administration of GRAFALON is strictly as per the physician's direction, usually as a controlled intravenous infusion.
Safety and Storage Guidelines
GRAFALON must be stored at 2C-8C and protected from freezing. Safety protocols require its administration in a hospital, supervised by healthcare professionals due to potential adverse reactions including leucopenia, thrombocytopenia, and infusion-related effects.
FAQ's of GRAFALON INJ:
Q: How is GRAFALON INJ administered?
A: GRAFALON INJ is given as an intravenous infusion in a hospital setting under the supervision of trained healthcare professionals.Q: What is the primary benefit of using GRAFALON INJ in organ transplantation?
A: GRAFALON helps prevent and treat acute rejection in transplant patients, especially in cases where steroid-based therapies have failed, by reducing the activity of immune T cells.Q: When should GRAFALON INJ not be used?
A: GRAFALON should not be administered to individuals with known hypersensitivity to rabbit proteins or any of its excipients.Q: What are the potential side effects of GRAFALON INJ?
A: Possible adverse effects include leucopenia, thrombocytopenia, infusion reactions, and an increased risk of infections. Monitoring by medical staff during administration is essential.Q: Where should GRAFALON INJ be stored?
A: GRAFALON INJ should be stored refrigerated between 2C-8C, and must not be frozen to preserve its efficacy.Q: What is the process for receiving GRAFALON INJ?
A: The process involves prescription by a specialist, hospital admission for supervised intravenous infusion, and careful monitoring for adverse effects during and after administration.Q: Who is GRAFALON INJ suitable for?
A: This medication is intended for adult patients who are undergoing solid organ transplantation and require prevention or treatment of steroid-resistant acute rejection.Tell us about your requirement
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संपर्क करें
- कार्यालय संख्या - 5, ग्राउंड फ्लोर, डी आर शॉपिंग सेंटर, दत्तपाड़ा रोड, एचडीएफसी बैंक के पास, बोरिवली पूर्व,मुंबई - 400066, महाराष्ट्र, भारत
- फ़ोन : 08045804946
- मर रणजीत सिंह (सीईओ व संस्थापक)
- मोबाइल : 08045804946
- medisus.pharma007@gmail.com
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